Imprinted Polymer Microrings as High-Performance Ultrasound Detectors in Photoacoustic Imaging

Low-noise small-size microring ultrasonic detectors for high-resolution photoacoustic imaging.

Small size polymer microring resonators have been exploited for photoacoustic (PA) imaging. To demonstrate the advantages of the wide acceptance angle of ultrasound detection of small size microrings, photoacoustic tomography (PAT), and delay-and-sum beamforming PA imaging was conducted. In PAT, we compared the imaging quality using different sizes of detectors with similar noise-equivalent pre...

Integrating Detectors for Photoacoustic Imaging

High-sensitivity and wide-directivity ultrasound detection using high Q polymer microring resonators.

Small size ultrahigh Q polymer microrings working at near visible wavelength have been experimentally demonstrated as ultralow noise ultrasound detectors with wide directivity at high frequencies (>20 MHz). By combining a resist reflow and a low bias continuous etching and passivation process in mold fabrication, imprinted polymer microrings with drastically improved sidewall smoothness were ob...

HematoPorphyrin Monomethyl Ether polymer contrast agent for ultrasound/photoacoustic dual-modality imaging-guided synergistic high intensity focused ultrasound (HIFU) therapy

This study is to prepare a hematoporphyrin monomethyl ether (HMME)-loaded poly(lactic-co-glycolic acid) (PLGA) microcapsules (HMME/PLGA), which could not only function as efficient contrast agent for ultrasound (US)/photoacoustic (PA) imaging, but also as a synergistic agent for high intensity focused ultrasound (HIFU) ablation. Sonosensitizer HMME nanoparticles were integrated into PLGA microc...

Photoacoustic Section Imaging with Integrating Detectors

Photoacoustic section imaging is a method for visualizing structures with optical contrast in selected layers of an extended object. In order to avoid resolution limitations that are due to commonly used ultrasound detectors of finite size, we propose the use of extended, integrating cylindrical elements for focusing the acoustic detection into the selected section. Two imaging methods based on...